Tamil Nadu's tourism industry is the second largest in India, with an annual growth rate of 16%. Tourism in Tamil Nadu is promoted by Tamil Nadu Tourism Development Corporation (TTDC), a Government of Tamil Nadu undertaking. The tagline adopted for promoting tourism in Tamil Nadu is Enchanting Tamil Nadu. Approximately 1,753,000 foreign and 50,647,000 domestic tourists visited the state in 2007.

Tamil Nadu is a land of varied beauty. It boasts some of the grandest Hindu temples of Dravidian architecture. These temples are of a distinct style renowned for their towering Gopurams. The Brihadishwara Temple in Thanjavur, built by the Cholas, the Airavateswara temple in Darasuram and the Shore Temple, along with the collection of other monuments in Mahabalipuram also called as Mamallaburam have been declared as UNESCO World Heritage Sites.

The largest Shiva Temple in Tamil Nadu is Nellaiappar Temple situated in the heart of Tirunelveli city. Madurai is home to one of the grandest Hindu temples in the World — Madurai Meenakshi Amman Temple. Rameshwaram, Kanchipuram and Palani are important pilgrimage sites for Hindus. Other popular temples in Tamil Nadu include those in Gangaikonda Cholapuram, melakadambur Chidambaram, Thiruvannaamalai, Tiruttani, Swamithoppe, Tiruchendur and Tiruvallur.

Tamil Nadu is also home to beautiful hill stations. Popular among them are Udhagamandalam (Ooty), Kodaikanal, Yercaud, Coonoor, Topslip, Valparai, Yelagiri and Manjolai. The Nilgiri hills, Palani hills, Shevaroy hills, Kolli Hills and Cardamom hills are all abodes of thick forests and wildlife. Mukurthi National Park & Kalakkad Mundanthurai Tiger Reserve are the two tiger reserves in the state. Tamil Nadu has many National Parks, Biosphere Reserves, Wildlife Sanctuaries, Elephant and Bird Sanctuaries, Reserved Forests, Zoos and Crocodile farms. Prominent among them are Mudumalai National Park, The Gulf of Mannar Biosphere Reserve, Indira Gandhi Wildlife Sanctuary and National Park, Vedanthangal Bird Sanctuary and Arignar Anna Zoological Park. The mangrove forests at Pichavaram are also eco-tourism spots of importance.

Kanyakumari, the southern most tip of peninsular India, is famous for its beautiful sunrise, Vivekananda Rock Memorial and Thiruvalluvar's statue built off the coastline. Marina Beach in Chennai is one of the longest beaches in the world. The stretch of beaches from Chennai to Mahabalipuram are home to many resorts, theme parks and eateries. The prominent waterfalls in the state are Courtallam, Hogenakal, Papanasam, Manimuthar, Thirparappu, Pykara and Silver Cascade. The Chettinad region of the state is renowned for its Palatial houses and cuisine. With medical care in Chennai, Vellore, Coimbatore and Madurai, Tamil Nadu has the largest numbers in Medical tourism in India.